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    Panacea, FL Commercial Real Estate for Sale

    66 results
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    Panacea Commercial Property with Bay View
    $284,900
    1,788 SF

    Panacea Commercial Property with Bay View

    1629 Coastal Hwy, Panacea, FL 32346

    Commercial property in Panacea, FL, with highway frontage and upgrades.

    • Prime commercial property with 0.95 acres and 250 feet of highway frontage.
    • 6,000 sqft building with extensive upgrades including new plumbing, electrical, and Hardie siding.
    • Located in the heart of Panacea on Dickerson Bay, seconds from boat ramps, deep‑water channels, and beaches.
    • Commercial‑grade stainless steel equipment conveys, suitable for various business ventures.
    • Ample parking and a durable metal roof.
    Updated: Oct 28, 2025
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    Highway 98 Commercial Land
    $30,000
    0.11 Acres

    Highway 98 Commercial Land

    lot 4 & 5 Coastal Hwy, Panacea, FL 32346

    Commercial lot with highway frontage and flexible zoning in Panacea.

    • Prime Highway 98 frontage with high visibility and strong traffic count.
    • C‑2 commercial zoning allows for flexible commercial, residential, or short‑term rental use.
    • City water, sewer, and power are available, simplifying the building process.
    • Located minutes from local restaurants and the Levy Bay boat ramp.
    • Partially cleared 100' x 100' lot ready for development.
    Updated: Feb 18
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    Waterfront Lot in Mashes Sands
    $79,900
    0.22 Acres

    Waterfront Lot in Mashes Sands

    Canal front lot with views, dock, and power in place.

    16 Sunrise Ln, Panacea, FL 32346
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    Panacea, FL Wooded Land
    Contact for pricing
    0.56 Acres

    Panacea, FL Wooded Land

    Wooded land with highway visibility, potential for commercial rezoning.

    21 Withlachoochee Ave, Panacea, FL 32346
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    Private Island Opportunity in Panacea
    $150,000
    230.00 Acres

    Private Island Opportunity in Panacea

    230-acre private island bordering river and government land in Panacea, Florida.

    Surf Rd, Panacea, FL 32346
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    Prime Land in Coastal Panacea
    $349,000
    0.87 Acres

    Prime Land in Coastal Panacea

    Versatile land with highway frontage, ideal for development.

    Division St, Panacea, FL 32346
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    Land in Tarpine Aviation Community
    $65,000
    1.60 Acres

    Land in Tarpine Aviation Community

    1.6-acre lot in fly-in community near Tarpine Airport.

    Cessna Ln, Panacea, FL 32346
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    Land in Coastal Panacea, FL
    Contact for pricing
    0.14 Acres

    Land in Coastal Panacea, FL

    Vacant lot in Panacea, near restaurants, fishing, and boating.

    Joe Mack Smith St, Panacea, FL 32346
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    Panacea, FL Commercial Property
    $249,000
    0.23 Acres

    Panacea, FL Commercial Property

    Commercial property with bay doors, car lift, and studio apartment.

    1138 Coastal Hwy Dr, Panacea, FL 32346
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    Prime Panacea Commercial Property
    $500,000
    0.78 Acres

    Prime Panacea Commercial Property

    Bank Building, High Visibility, 0.78 Acres

    104 Coastal Hwy, Panacea, FL 32346
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    Coastal Highway Retail Opportunity
    $125,000
    1,800 SF

    Coastal Highway Retail Opportunity

    Prime Panacea Retail Space, 1800 sq ft

    1331 Coastal Hwy, Panacea, FL 32346
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    Panacea Waterfront Commercial Opportunity
    $289,000
    6,720 SF

    Panacea Waterfront Commercial Opportunity

    Prime Panacea location, 6720 sq ft, 0.92 acres.

    1353 Coastal Hwy, Panacea, FL 32346
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    Panacea Commercial Waterfront Opportunity
    $169,000
    7,056 SF

    Panacea Commercial Waterfront Opportunity

    Prime Coastal Highway location, 7,056 sq ft.

    1325 Coastal Hwy, Panacea, FL 32346
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    Florida Coastal Convenience Stores
    $1,800,000

    Florida Coastal Convenience Stores

    Turnkey Dual Liquor Store Investment

    1306 Coastal Hwy, Panacea, FL 32346
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    Panacea Commercial Property w/ Apartment
    $249,000
    659 SF

    Panacea Commercial Property w/ Apartment

    Prime Coastal Hwy Location, Versatile Space

    1138 Coastal Hwy Dr, Panacea, FL 32346
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    Panacea Commercial Lot - Highway Frontage
    $30,000
    0.22 Acres

    Panacea Commercial Lot - Highway Frontage

    Prime Panacea location, highway frontage, build your business.

    Hwy, Panacea, FL 32346
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    Panacea Commercial Lot - Highway Frontage
    $30,000
    0.22 Acres

    Panacea Commercial Lot - Highway Frontage

    Prime .22-acre lot, 70ft highway frontage.

    Hwy, Panacea, FL 32346
    View details

    Panacea, FL Commercial Real Estate Investment Opportunities Market Analysis

    Explore 17 commercial real estate for sale in Panacea, FL, showcased through 66 active listings on our real estate platform. These investment opportunities span a total of 10,375,556 square feet of properties for sale, with an estimated market value of $2,599,800.

    Sale prices for business properties in Panacea, FL start at $30,000, averaging $185,700, and reaching up to $500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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