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Panacea, FL Commercial Real Estate for Sale

10 results
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Panacea, FL Commercial Property
$249,000
0.23 Acres

Panacea, FL Commercial Property

1138 Coastal Hwy Dr, Panacea, FL 32346

Commercial property with bay doors, car lift, and studio apartment.

  • High‑traffic location on US HWY 98 (Coastal HWY) with great road frontage.
  • Versatile commercial property suitable for various business ventures.
  • Equipped with two bay doors and a car lift.
  • Includes a 1‑bedroom, 1‑bath studio apartment at the rear.
  • Double lots providing ample space.
Updated: Nov 17, 2025
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Highway Frontage Commercial Building
$284,900
6,080 SF

Highway Frontage Commercial Building

1629 Coastal Hwy, Panacea, FL 32346

Commercial building with highway frontage, suitable for various business ventures.

  • Prime commercial property with bay view and 250 feet of highway frontage.
  • 6,000 sqft building on 0.95 acres in the heart of Panacea.
  • Extensive upgrades including new plumbing, electrical, Hardie siding, and metal roof.
  • Commercial‑grade stainless steel equipment included.
  • Located seconds from three boat ramps, deep‑water channels, and beaches.
Updated: Oct 28, 2025
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Panacea Commercial Property w/ Apartment
$249,000
659 SF

Panacea Commercial Property w/ Apartment

Prime Coastal Hwy Location, Versatile Space

1138 Coastal Hwy Dr, Panacea, FL 32346
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Prime Panacea Commercial Property
$500,000
0.78 Acres

Prime Panacea Commercial Property

Bank Building, High Visibility, 0.78 Acres

104 Coastal Hwy, Panacea, FL 32346
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Coastal Highway Retail Opportunity
$125,000
1,800 SF

Coastal Highway Retail Opportunity

Prime Panacea Retail Space, 1800 sq ft

1331 Coastal Hwy, Panacea, FL 32346
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Panacea Waterfront Commercial Opportunity
$289,000
6,720 SF

Panacea Waterfront Commercial Opportunity

Prime Panacea location, 6720 sq ft, 0.92 acres.

1353 Coastal Hwy, Panacea, FL 32346
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Panacea Commercial Waterfront Opportunity
$169,000
7,056 SF

Panacea Commercial Waterfront Opportunity

Prime Coastal Highway location, 7,056 sq ft.

1325 Coastal Hwy, Panacea, FL 32346
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Panacea Commercial Lot - Highway Frontage
$30,000
0.22 Acres

Panacea Commercial Lot - Highway Frontage

Prime Panacea location, highway frontage, build your business.

Hwy, Panacea, FL 32346
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Panacea Commercial Lot - Highway Frontage
$30,000
0.22 Acres

Panacea Commercial Lot - Highway Frontage

Prime .22-acre lot, 70ft highway frontage.

Hwy, Panacea, FL 32346
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Florida Coastal Convenience Stores
$1,800,000

Florida Coastal Convenience Stores

Turnkey Dual Liquor Store Investment

1306 Coastal Hwy, Panacea, FL 32346
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Based on your search, we've compiled 150 Potential Opportunities for your consideration. Besides 10 Active listings in Panacea, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 135 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Sopchoppy Land with Highway Frontage
$49,900
1.85 Acres

Sopchoppy Land with Highway Frontage

1.85 acre lot with frontage on Highway 319.

Sopchoppy Hwy, Sopchoppy, FL 32358
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Crawfordville Commercial Land Opportunity
$474,900
9.88 Acres

Crawfordville Commercial Land Opportunity

9.88 acre commercial property in a rapidly growing market.

2820 Coastal Hwy, Crawfordville, FL 32327
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Crawfordville Commercial Land Opportunity
$474,900
9.88 Acres

Crawfordville Commercial Land Opportunity

9.88 acre commercial property in a rapidly growing market.

2836 Coastal Hwy, Crawfordville, FL 32327
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Waterfront Lots with River Access
$485,000
0.62 Acres

Waterfront Lots with River Access

Five lots with water access, including riverfront and canal options.

90 Mathis Rd, Sopchoppy, FL 32358
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Land in Coastal Panacea
$349,000
0.87 Acres

Prime Land in Coastal Panacea

Versatile land with highway frontage, ideal for development.

Division St, Panacea, FL 32346
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Explore Off-Market Properties in Panacea, FL

Consider similar Off-Market properties in Panacea, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

Hwy

Hwy

Commercial real estate • 0.22 Acres
Value Estimation by Request
Hwy, Panacea, FL 32346
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1306 Coastal Hwy

1306 Coastal Hwy

Individual retail properties
Value Estimation by Request
1306 Coastal Hwy, Panacea, FL 32346
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1138 Coastal Hwy Dr

1138 Coastal Hwy Dr

Commercial real estate • 659 SF
Value Estimation by Request
1138 Coastal Hwy Dr, Panacea, FL 32346
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Hwy

Hwy

Commercial real estate • 0.22 Acres
Value Estimation by Request
Hwy, Panacea, FL 32346
View details
43 Rock Lndg Rd

43 Rock Lndg Rd

MANUFACTURING (LIGHT) • 780 SF
Value Estimation by Request
43 Rock Lndg Rd, Panacea, FL 32346-2331
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Coastal Hwy

Coastal Hwy

HEAVY MANUFACTURING • 0.41 Acres
Value Estimation by Request
Coastal Hwy, Panacea, FL 32346
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Coastal Hwy

Coastal Hwy

HEAVY MANUFACTURING • 0.21 Acres
Value Estimation by Request
Coastal Hwy, Panacea, FL 32346
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19 Wakulla Cir

19 Wakulla Cir

INDUSTRIAL (GENERAL) • 3,501 SF
Value Estimation by Request
19 Wakulla Cir, Panacea, FL 32346-2656
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1616 Coastal Hwy

1616 Coastal Hwy

MANUFACTURING (LIGHT) • 5,004 SF
Value Estimation by Request
1616 Coastal Hwy, Panacea, FL 32346
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15 Otter Lk Rd

15 Otter Lk Rd

MANUFACTURING (LIGHT) • 1,952 SF
Value Estimation by Request
15 Otter Lk Rd, Panacea, FL 32346-2058
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1532 Coastal Hwy

1532 Coastal Hwy

HEAVY MANUFACTURING • 2,500 SF
Value Estimation by Request
1532 Coastal Hwy, Panacea, FL 32346-2154
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32 Joe Mack Smith St

32 Joe Mack Smith St

MANUFACTURING (LIGHT) • 1,420 SF
Value Estimation by Request
32 Joe Mack Smith St, Panacea, FL 32346-1914
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19 Dillworth Dr

19 Dillworth Dr

WAREHOUSE, STORAGE • 0.25 Acres
Value Estimation by Request
19 Dillworth Dr, Panacea, FL 32346
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56 Jer Be Lou Blvd

56 Jer Be Lou Blvd

FOOD PACKING, PACKING PLANT • 7,450 SF
Value Estimation by Request
56 Jer Be Lou Blvd, Panacea, FL 32346-2070
View details

Panacea, FL Commercial Real Estate Investment Opportunities Market Analysis

Explore 91 commercial real estate investment opportunities in Panacea, FL with 10 listings featured on our commercial real estate marketplace. The current inventory includes 13,346,889 square feet of properties with an estimated value of $19,999,425.

Estimated prices for commercial real estate in Panacea, FL begin at $30,000, with an average of $253,157 and extend to $1,965,000.

In Panacea, FL, current investment values show:

  • Land positioned at $121,287
  • Retail properties measuring $412,195
  • Residential land & home lots assessed at $103,111
  • Office Properties & Spaces calculated at $215,000
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