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    Lee County, NC Commercial Real Estate for Lease

    31 results
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    Historic Sanford Home For Rent
    $48,000
    3,550 SF

    Historic Sanford Home For Rent

    202 W Main Street, Sanford, NC 27332

    Restored historic home suitable for office or event space.

    • Exquisitely restored historic home (Ca 1880) with extensive updates including new foundation, roof, HVAC, electric, plumbing, kitchen, and baths.
    • Large 1.19 acre lot suitable for events and additional parking.
    • Zoned C‑2, making it ideal for a professional office or event space.
    • Notable historical significance: built by railroad official Frank Pierce and later owned by attorney and NC Attorney General A.A.F. Seawell.
    • Located in the desirable Jonesboro Heights section of Sanford.
    Updated: Mar 4
    View details
    Former Acura Dealership For Lease
    $351,320
    17,566 SF

    Former Acura Dealership For Lease

    3590 Nc 87, Sanford, NC 27332

    Fully equipped automotive center with customer lounge and parts storage.

    • Fully equipped automotive center, ready for immediate operation.
    • Includes 16 Rotary lifts and Hunter Alignment machine.
    • Features Hunter tire changer, balancer, and road force balancer.
    • All utilities included in the lease.
    • Opportunity to handle 50+ cars per month from current dealer.
    Updated: Oct 16, 2025
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    Sanford Retail Space For Rent
    $18,000 /Mo
    1,000 SF

    Sanford Retail Space For Rent

    1,000 sq ft retail space near Walmart and Hwy 87.

    352 Wilson Road unit: 360, Sanford, NC 27332
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    Unique Downtown Sanford Retail Space
    $3,350 /Mo
    19,500 SF

    Unique Downtown Sanford Retail Space

    Renovated retail space with hardwood floors and exposed brick.

    102 S. Steele St, Sanford, NC 27330
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    Sanford Industrial Building For Lease
    $7 SF/Yr
    52,500 SF

    Sanford Industrial Building For Lease

    52,500 SF industrial building suitable for manufacturing or distribution.

    908 Jr Industrial Dr, Sanford, NC 27332
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    Sanford Mixed-Use Property for Lease
    $5,500 /Mo
    2,451 SF

    Sanford Mixed-Use Property for Lease

    Flexible mixed-use property near downtown Sanford with office, warehouse, and apartment.

    209 Sycamore St, Sanford, NC 27330
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    Sanford Industrial Space with Yard
    $12 SF/Yr
    20,880 SF

    Sanford Industrial Space with Yard

    Industrial space with laydown yard available for lease.

    3030 Lee Ave, Sanford, NC 27332
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    Sanford Industrial Facility For Lease
    Contact for pricing
    28,135 SF

    Sanford Industrial Facility For Lease

    Versatile industrial facility with warehouse, production, and operational space.

    5825 Clyde Rhyne Dr, Sanford, NC 27330
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    Sanford Industrial Space For Lease
    $6 SF/Yr
    135,580 SF

    Sanford Industrial Space For Lease

    Industrial spaces for lease with downtown Sanford access.

    633 Chatham St, Sanford, NC 27330
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    Sanford Flex Industrial Building Available
    $7 SF/Yr
    25,754 SF

    Sanford Flex Industrial Building Available

    25,754 SF flex industrial building for lease in Sanford, NC.

    2907 Lee Avenue, Sanford, NC 27330
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    Sanford Warehouse Space Available
    $9 SF/Yr
    16,000 SF

    Sanford Warehouse Space Available

    16,000 SF warehouse space for lease near BUS-421.

    3307 Lee Avenue, Sanford, NC 27330
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    Sanford Warehouse with Fenced Storage
    $9 SF/Yr
    16,000 SF

    Sanford Warehouse with Fenced Storage

    16,000 SF warehouse with outside storage available Q4 2025.

    3307 Lee Avenue, Sanford, NC 27330
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    Retail Pad in Growing Area
    Contact for pricing

    Retail Pad in Growing Area

    Retail pad available for lease in rapidly growing Tramway area.

    Sanford, NC 27330
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    Sanford Industrial/Flex Build-to-Suit Opportunity
    Contact for pricing
    100,000 SF

    Sanford Industrial/Flex Build-to-Suit Opportunity

    Industrial/Flex space for lease with highway access and flexible layout.

    0 Lee Avenue, Sanford, NC 27332
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    Sanford Warehouse Space Available
    $1.00 SF/Yr
    150,000 SF

    Sanford Warehouse Space Available

    40,000 SF warehouse space in growing downtown Sanford.

    513 Wicker Street, Sanford, NC 27330
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    Office Space for Lease
    Contact for pricing

    Office Space for Lease

    Office space available near Central Carolina Hospital in Sanford, NC.

    611 Carthage St, Sanford, NC 27330
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    Freestanding Restaurant in Sanford, NC
    Contact for pricing

    Freestanding Restaurant in Sanford, NC

    Freestanding second-generation restaurant with high visibility and ample parking.

    Sanford, NC 27332
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    Retail Development Land For Lease
    Contact for pricing

    Retail Development Land For Lease

    1.02 acre commercial land for lease in Sanford, NC.

    5110 NC Hwy 87, Sanford, NC 27332
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    Sanford Flex Space For Lease
    Contact for pricing
    19,250 SF

    Sanford Flex Space For Lease

    3,006 SF flex space in Moore Business Park.

    201-225 Commercial Court, Sanford, NC 27330
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    Office Space Available For Rent
    Contact for pricing
    6,645 SF

    Office Space Available For Rent

    Single tenant office space available, totaling 6,645 square feet.

    1024 S Horner Blvd, Sanford, NC 27330
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    Sanford Industrial Space with Storage
    Contact for pricing
    8,400 SF

    Sanford Industrial Space with Storage

    7,400 SF industrial space with fenced laydown storage.

    3105 Hal Siler Dr, Sanford, NC 27332
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    Free Standing Bank Building
    Contact for pricing
    5,365 SF

    Free Standing Bank Building

    Bank building with drive-thru and redevelopment potential on 0.90-acre.

    1001 South Horner Boulevard, Sanford, NC 27330
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    Sanford Industrial Building with Highway Access
    $4 SF/Yr
    91,366 SF

    Sanford Industrial Building with Highway Access

    91,366 SF industrial building ideal for warehousing and distribution.

    2613 Lee Ave, Sanford, NC
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    Sanford Industrial Development Opportunity
    Contact for pricing
    1,000,000 SF

    Sanford Industrial Development Opportunity

    Master-planned industrial development with build-to-suit options available.

    Rod Sullivan Road, Sanford, NC 27330
    View details

    Lee County, NC Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Lee County, NC with 31 listings featured on our commercial real estate exchange. The current inventory includes 8,249,392,800 square feet of properties with an estimated lease value of $298 SF/Yr.

    Estimated lease rates for Commercial real estate in Lee County, NC begin at $1.00 SF/Yr, with an average of $59 SF/Yr and extend to $216 SF/Yr.
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